Pregnancy and Neonatal Diabetes Outcomes in Remote Australia: The PANDORA study - An observational birth cohort

L Maple-Brown; IL Lee; D Longmore; F Barzi; C Connors; JA Boyle; E Moore; C Whitbread; M Kirkwood; S Graham; V Hampton; A Simmonds; P Van Dokkum; J Kelaart; S Thomas; S Chitturi; S Eades; S Corpus; M Lynch; ZX Lu; K O'Dea; P Zimmet; J Oats; HD McIntyre; ADH Brown; JE Shaw; K Dempsey; S Svenson; L Wood; L Davis; G Dent; M Stone; M Harris; C Inglis

Journal article

Pregnancy and Neonatal Diabetes Outcomes in Remote Australia: The PANDORA study - An observational birth cohort

L Maple-Brown, IL Lee, D Longmore, F Barzi, C Connors, JA Boyle, E Moore, C Whitbread, M Kirkwood, S Graham, V Hampton, A Simmonds, P Van Dokkum, J Kelaart, S Thomas, S Chitturi, S Eades, S Corpus, M Lynch, ZX Lu Show all

International Journal of Epidemiology | OXFORD UNIV PRESS | Published : 2019

DOI: 10.1093/ije/dyy245

Abstract

Background In Australia's Northern Territory, 33% of babies are born to Indigenous mothers, who experience high rates of hyperglycemia in pregnancy. We aimed to determine the extent to which pregnancy outcomes for Indigenous Australian women are explained by relative frequencies of diabetes type [type 2 diabetes (T2DM) and gestational diabetes (GDM)]. Methods This prospective birth cohort study examined participants recruited from a hyperglycemia in pregnancy register. Baseline data collected were antenatal and perinatal clinical information, cord blood and neonatal anthropometry. Of 1135 women (48% Indigenous), 900 had diabetes: 175 T2DM, 86 newly diagnosed diabetes in pregnancy (DIP) and 6..

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University of Melbourne Researchers

I-Lynn Lee Author

Danielle Longmore Author

Sandra Eades Author

Jeremy Oats Author

Related Projects (2)

PREGNANCY AND NEONATAL DIABETES OUTCOMES IN REMOTE AUSTRALIA (PANDORA) COHORT

The PANDORA study is a longitudinal birth cohort study recruited from a clinical register of Northern Territory women with diabetes in pregn..

NTDIP: NORTHERN TERRITORY DIABETES IN PREGNANCY PROJECT

Diabetes in pregnancy provides exposure to high sugar levels before birth which can result in the child developing obesity, diabetes and car..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

We gratefully acknowledge all PANDORA study staff and participants, including Stacey Svenson, Lynice Wood and Liz Davis, as well as NT DIP investigators, partners, staff and clinical reference groups, NT health professionals from NT Department of Health hospitals, remote primary health care, Healthy Living NT and Aboriginal Community Controlled Health Organisations. Investigators of the NT DIP Partnership in addition to those named as authors are G. Dent, M. Stone, M. Harris, C. Inglis and K. Dempsey. This work was supported by the National Health and Medical Research Council of Australia (NHMRC Partnership Project Grant #1032116, NHMRC #1078333). Additional support (including pilot funding) was received from NHMRC Program Grant #631947. L.M.B. was supported by NHMRC Fellowship #605837 and NHMRC Practitioner Fellowship #1078477; I.L. was supported by an Australian Postgraduate award and Menzies scholarship; D. L. was supported by NHMRC Postgraduate scholarship #1038372; J.A.B. was supported by NHMRC Career Development Fellowship; A.B. was supported by a Sylvia and Charles Viertel Senior Medical Research Fellowship; J.E.S. was supported by NHMRC Fellowship #1079438. The views expressed in this publication are those of the authors and do not reflect the views of the NHMRC. The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript.